THE MASTERY OF DETAILS IN THE WORKFLOW OF MATERIALS MACHINE LEARNING


Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation

Abstract Deubiquitinating enzymes (DUBs) are key regulators of cellular homoeostasis, and their dysregulation is associated with several human diseases.The ovarian tumour protease (OTU) family of DUBs are biochemically well-characterised and of Ingredient Bins therapeutic interest, yet only a few tool compounds exist to study their cellular functio

read more

Vacuolin-1 enhances RA-induced differentiation of human myeloblastic leukemia cells: evidence for involvement of a CD11b/FAK/LYN/SLP-76 axis subject to endosomal regulation that drives late differentiation steps

Abstract Background Retinoic acid(RA), an embryonic morphogen, regulates cell differentiation.Endocytosis regulates receptor signaling that governs such RA-directed cellular processes.Vacuolin-1 is a small molecule that disrupts endocytosis, motivating Gels interest in its effect on RA-induced differentiation/arrest.In HL-60 myeloblastic-leukemia c

read more

Factor structure and reliability of the symptom measurement of post-stroke depression in the rehabilitation stage

Abstract Background The incidence of Post Stroke Depression (PSD) in the Rehabilitation Stage is high, which can bring serious physical and psychological disorders to patients.However, there is still a lack of targeted tools for screening PSD in the rehabilitation stage.Therefore, the aim of this study was to evaluate the factor structure and relia

read more

Exploration of Lifestyle Choices, Reproductive Health Knowledge, and Polycystic Ovary Syndrome (PCOS) Awareness Among Female Emirati University Students

Sreepoorna Pramodh College of Natural and Health Sciences, Zayed University, Dubai, United Arab EmiratesCorrespondence: Sreepoorna PramodhZayed University, C-L1-41, Dubai Campus, Academic City, Dubai 19282, United Arab EmiratesTel +97144021736Fax +97144021008Email [email protected]: Healthy lifestyle and adequate reproductive health

read more